Cargando…

Hypoxia induces epithelial-mesenchymal transition via activation of SNAI1 by hypoxia-inducible factor -1α in hepatocellular carcinoma

BACKGROUND: High invasion and metastasis are the primary factors causing poor prognosis of patients with hepatocellular carcinoma (HCC). However, the molecular mechanisms underlying these biological behaviors have not been completely elucidated. In this study, we investigate the molecular mechanism...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Lin, Huang, Gang, Li, Xiaowu, Zhang, Yujun, Jiang, Yan, Shen, Junjie, Liu, Jia, Wang, Qingliang, Zhu, Jin, Feng, Xiaobin, Dong, Jiahong, Qian, Cheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614870/ https://www.ncbi.nlm.nih.gov/pubmed/23496980 http://dx.doi.org/10.1186/1471-2407-13-108

Ejemplares similares

SNAI1 recruits HDAC1 to suppress SNAI2 transcription during epithelial to mesenchymal transition
por: Sundararajan, Vignesh, et al.
Publicado: (2019)

FoxM1 promotes epithelial-mesenchymal transition of hepatocellular carcinoma by targeting Snai1
por: Yu, Chun-Peng, et al.
Publicado: (2017)

Hypoxia-Induced Epithelial-Mesenchymal Transition in Cancers: HIF-1α and Beyond
por: Tam, Shing Yau, et al.
Publicado: (2020)

FOXF1 Induces Epithelial-Mesenchymal Transition in Colorectal Cancer Metastasis by Transcriptionally Activating SNAI1()()
por: Wang, Shuyang, et al.
Publicado: (2018)

Hypoxia Induces Epithelial-Mesenchymal Transition in Follicular Thyroid Cancer: Involvement of Regulation of Twist by Hypoxia Inducible Factor-1α
por: Yang, Yeon Ju, et al.
Publicado: (2015)

TET1 may contribute to hypoxia-induced epithelial to mesenchymal transition of endometrial epithelial cells in endometriosis
por: Wu, Jingni, et al.
Publicado: (2020)

Hypoxia Promotes Epithelial - Mesenchymal Transition of Hepatocellular Carcinoma Cells via Inducing GLIPR-2 Expression
por: Huang, Shao-guang, et al.
Publicado: (2013)

Propofol Reversed Hypoxia-Induced Docetaxel Resistance in Prostate Cancer Cells by Preventing Epithelial–Mesenchymal Transition by Inhibiting Hypoxia-Inducible Factor 1α
por: Qian, Jiang, et al.
Publicado: (2018)

Hypoxia-Induced Epithelial-Mesenchymal Transition Is Involved in Bleomycin-Induced Lung Fibrosis
por: Guo, Liang, et al.
Publicado: (2015)

Hypoxia Activated EGFR Signaling Induces Epithelial to Mesenchymal Transition (EMT)
por: Misra, Ashish, et al.
Publicado: (2012)

Effect of PACAP on Hypoxia-Induced Angiogenesis and Epithelial–Mesenchymal Transition in Glioblastoma
por: Maugeri, Grazia, et al.
Publicado: (2021)

Control of the Epithelial-to-Mesenchymal Transition and Cancer Metastasis by Autophagy-Dependent SNAI1 Degradation
por: Zada, Sahib, et al.
Publicado: (2019)

TET1 regulates hypoxia-induced epithelial-mesenchymal transition by acting as a co-activator
por: Tsai, Ya-Ping, et al.
Publicado: (2014)

Notch1 signaling induces epithelial-mesenchymal transition in lens epithelium cells during hypoxia
por: Liu, Lei, et al.
Publicado: (2017)

SENP-1 enhances hypoxia-induced proliferation of rat pulmonary artery smooth muscle cells by regulating hypoxia-inducible factor-1α
por: ZHOU, FANG, et al.
Publicado: (2016)

Hypoxia-induced epithelial-mesenchymal transition and fibrosis for the development of breast capsular contracture
por: Kuo, Yao-Lung, et al.
Publicado: (2019)

Hypoxia-inducible factor-1α regulates epithelial-to-mesenchymal transition in paraquat-induced pulmonary fibrosis by activating lysyl oxidase
por: Lu, Jian, et al.
Publicado: (2018)

DACH1 inhibits SNAI1-mediated epithelial–mesenchymal transition and represses breast carcinoma metastasis
por: Zhao, F, et al.
Publicado: (2015)

Role of epithelial-mesenchymal transition factor SNAI1 and its targets in ovarian cancer aggressiveness
por: Suzuki, Tise, et al.
Publicado: (2023)

The critical role of glucose deprivation in epithelial-mesenchymal transition in hepatocellular carcinoma under hypoxia
por: Jo, Hanhee, et al.
Publicado: (2020)

AIB1 Cooperates with ERα to Promote Epithelial Mesenchymal Transition in Breast Cancer through SNAI1 Activation
por: Wang, Miao, et al.
Publicado: (2013)

STAT3 regulates hypoxia-induced epithelial mesenchymal transition in oesophageal squamous cell cancer
por: CUI, YAO, et al.
Publicado: (2016)

β-Patchoulene represses hypoxia-induced proliferation and epithelial-mesenchymal transition of liver cancer cells
por: Tu, Huahua, et al.
Publicado: (2022)

Paeoniflorin prevents hypoxia-induced epithelial–mesenchymal transition in human breast cancer cells
por: Zhou, Zhenyu, et al.
Publicado: (2016)

MicroRNA-30a Regulation of Epithelial-Mesenchymal Transition in Diabetic Cataracts Through Targeting SNAI1
por: Zhang, Lu, et al.
Publicado: (2017)

Wheatgrass extract inhibits hypoxia-inducible factor-1-mediated epithelial-mesenchymal transition in A549 cells
por: Do, Nam Yong, et al.
Publicado: (2017)

Hypoxia induces endothelial-mesenchymal transition in pulmonary vascular remodeling
por: Zhang, Bo, et al.
Publicado: (2018)

TLX3 repressed SNAI1-induced epithelial-mesenchymal transition by directly constraining STAT3 phosphorylation and functionally sensitized 5-FU chemotherapy in hepatocellular carcinoma
por: Wang, Cong, et al.
Publicado: (2019)

Ginsenoside 20(S)-Rg3 Targets HIF-1α to Block Hypoxia-Induced Epithelial-Mesenchymal Transition in Ovarian Cancer Cells
por: Liu, Ting, et al.
Publicado: (2014)

The hypoxia factor Hif-1α controls neural crest chemotaxis and epithelial to mesenchymal transition
por: Barriga, Elias H., et al.
Publicado: (2013)

Retraction: AIB1 Cooperates with ERα to Promote Epithelial Mesenchymal Transition in Breast Cancer through SNAI1 Activation
Publicado: (2021)

Hypoxia-inducible factor-1α induces CX3CR1 expression and promotes the epithelial to mesenchymal transition (EMT) in ovarian cancer cells
por: Singh, Santosh Kumar, et al.
Publicado: (2019)

SNAI2 is induced by transforming growth factor-β1, but is not essential for epithelial-mesenchymal transition in human keratinocyte HaCaT cells
por: Miyake, Yuki, et al.
Publicado: (2021)

Vincamine Ameliorates Epithelial-Mesenchymal Transition in Bleomycin-Induced Pulmonary Fibrosis in Rats; Targeting TGF-β/MAPK/Snai1 Pathway
por: Alaaeldin, Rania, et al.
Publicado: (2023)

Extracellular ATP promotes breast cancer invasion and epithelial‐mesenchymal transition via hypoxia‐inducible factor 2α signaling
por: Yang, Hui, et al.
Publicado: (2019)

Hypoxia, Snail and incomplete epithelial–mesenchymal transition in breast cancer
por: Lundgren, K, et al.
Publicado: (2009)

Hypoxia, Epithelial-Mesenchymal Transition, and TET-Mediated Epigenetic Changes
por: Kao, Shih-Han, et al.
Publicado: (2016)

Epigenetics, TET proteins, and hypoxia in epithelial-mesenchymal transition and tumorigenesis
por: Chen, Hsiao-Fan, et al.
Publicado: (2016)

LncRNA TRERNA1 Function as an Enhancer of SNAI1 Promotes Gastric Cancer Metastasis by Regulating Epithelial-Mesenchymal Transition
por: Wu, Huazhang, et al.
Publicado: (2017)

Regulation of COX-2 expression and epithelial-to-mesenchymal transition by hypoxia-inducible factor-1α is associated with poor prognosis in hepatocellular carcinoma patients post TACE surgery
por: HUANG, MINGSHENG, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_c8u8eh6ha8ocjjio72uamhk0jm