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Hypoxia induces epithelial-mesenchymal transition via activation of SNAI1 by hypoxia-inducible factor -1α in hepatocellular carcinoma

BACKGROUND: High invasion and metastasis are the primary factors causing poor prognosis of patients with hepatocellular carcinoma (HCC). However, the molecular mechanisms underlying these biological behaviors have not been completely elucidated. In this study, we investigate the molecular mechanism...

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Detalles Bibliográficos
Autores principales: Zhang, Lin, Huang, Gang, Li, Xiaowu, Zhang, Yujun, Jiang, Yan, Shen, Junjie, Liu, Jia, Wang, Qingliang, Zhu, Jin, Feng, Xiaobin, Dong, Jiahong, Qian, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614870/
https://www.ncbi.nlm.nih.gov/pubmed/23496980
http://dx.doi.org/10.1186/1471-2407-13-108

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