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Genecentric: a package to uncover graph-theoretic structure in high-throughput epistasis data
BACKGROUND: New technology has resulted in high-throughput screens for pairwise genetic interactions in yeast and other model organisms. For each pair in a collection of non-essential genes, an epistasis score is obtained, representing how much sicker (or healthier) the double-knockout organism will...
Autores principales: | Gallant, Andrew, Leiserson, Mark DM, Kachalov, Maxim, Cowen, Lenore J, Hescott, Benjamin J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614884/ https://www.ncbi.nlm.nih.gov/pubmed/23331614 http://dx.doi.org/10.1186/1471-2105-14-23 |
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