Somatic Mutations in Exocrine Pancreatic Tumors: Association with Patient Survival

KRAS mutations are major factors involved in initiation and maintenance of pancreatic tumors. The impact of different mutations on patient survival has not been clearly defined. We screened tumors from 171 pancreatic cancer patients for mutations in KRAS and CDKN2A genes. Mutations in KRAS were dete...

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Detalles Bibliográficos
Autores principales: Rachakonda, P. Sivaramakrishna, Bauer, Andrea S., Xie, Huaping, Campa, Daniele, Rizzato, Cosmeri, Canzian, Federico, Beghelli, Stefania, Greenhalf, William, Costello, Eithne, Schanne, Michaela, Heller, Anette, Scarpa, Aldo, Neoptolemos, John P., Werner, Jens, Büchler, Markus, Hoheisel, Jörg D., Hemminki, Kari, Giese, Nathalia, Kumar, Rajiv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614935/
https://www.ncbi.nlm.nih.gov/pubmed/23565280
http://dx.doi.org/10.1371/journal.pone.0060870

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