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Molecular Karyotyping of Human Single Sperm by Array- Comparative Genomic Hybridization
No valid method is currently available to analyze the entire genome of sperm, including aneuploidies and structural chromosomal alterations. Here we describe the optimization and application of array-Comparative Genomic Hybridization (aCGH) on single human sperm. The aCGH procedure involves screenin...
Autores principales: | Patassini, Cristina, Garolla, Andrea, Bottacin, Alberto, Menegazzo, Massimo, Speltra, Elena, Foresta, Carlo, Ferlin, Alberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614952/ https://www.ncbi.nlm.nih.gov/pubmed/23565289 http://dx.doi.org/10.1371/journal.pone.0060922 |
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