Cargando…

Host Gene Expression Profiling and In Vivo Cytokine Studies to Characterize the Role of Linezolid and Vancomycin in Methicillin-Resistant Staphylococcus aureus (MRSA) Murine Sepsis Model

Linezolid (L), a potent antibiotic for Methicillin Resistant Staphylococcus aureus (MRSA), inhibits bacterial protein synthesis. By contrast, vancomycin (V) is a cell wall active agent. Here, we used a murine sepsis model to test the hypothesis that L treatment is associated with differences in bact...

Descripción completa

Detalles Bibliográficos
Autores principales: Sharma-Kuinkel, Batu K., Zhang, Yurong, Yan, Qin, Ahn, Sun Hee, Fowler, Vance G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614971/
https://www.ncbi.nlm.nih.gov/pubmed/23565251
http://dx.doi.org/10.1371/journal.pone.0060463