Bleomycin Induces Molecular Changes Directly Relevant to Idiopathic Pulmonary Fibrosis: A Model for “Active” Disease

The preclinical model of bleomycin-induced lung fibrosis, used to investigate mechanisms related to idiopathic pulmonary fibrosis (IPF), has incorrectly predicted efficacy for several candidate compounds suggesting that it may be of limited value. As an attempt to improve the predictive nature of th...

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Detalles Bibliográficos
Autores principales: Peng, Ruoqi, Sridhar, Sriram, Tyagi, Gaurav, Phillips, Jonathan E., Garrido, Rosario, Harris, Paul, Burns, Lisa, Renteria, Lorena, Woods, John, Chen, Leena, Allard, John, Ravindran, Palanikumar, Bitter, Hans, Liang, Zhenmin, Hogaboam, Cory M., Kitson, Chris, Budd, David C., Fine, Jay S., Bauer, Carla MT., Stevenson, Christopher S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614979/
https://www.ncbi.nlm.nih.gov/pubmed/23565148
http://dx.doi.org/10.1371/journal.pone.0059348

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