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Linoleic Acid Stimulates [Ca(2+)]i Increase in Rat Pancreatic Beta-Cells through Both Membrane Receptor- and Intracellular Metabolite-Mediated Pathways

The role of the free fatty acid (FFA) receptor and the intracellular metabolites of linoleic acid (LA) in LA-stimulated increase in cytosolic free calcium concentration ([Ca(2+)]i) was investigated. [Ca(2+)]i was measured using Fura-2 as indicator in rat pancreatic β-cells in primary culture. LA (20...

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Detalles Bibliográficos
Autores principales: Zhao, Yufeng, Wang, Li, Qiu, Jianhua, Zha, Dingjun, Sun, Qiang, Chen, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614997/
https://www.ncbi.nlm.nih.gov/pubmed/23565210
http://dx.doi.org/10.1371/journal.pone.0060255

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