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Liposomal Lipopolysaccharide Initiates TRIF-Dependent Signaling Pathway Independent of CD14

Lipopolysaccharide (LPS) is recognized by CD14 with Toll-like receptor 4 (TLR4), and initiates 2 major pathways of TLR4 signaling, the MyD88-dependent and TRIF-dependent signaling pathways. The MyD88-dependent pathway induces inflammatory responses such as the production of TNF-α, IL-6, and IL-12 vi...

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Detalles Bibliográficos
Autores principales: Watanabe, Sachiko, Kumazawa, Yoshio, Inoue, Joe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615118/
https://www.ncbi.nlm.nih.gov/pubmed/23565187
http://dx.doi.org/10.1371/journal.pone.0060078

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