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ICOS controls Foxp3(+) regulatory T-cell expansion, maintenance and IL-10 production during helminth infection

Foxp3(+) regulatory T (Treg) cells are key immune regulators during helminth infections, and identifying the mechanisms governing their induction is of principal importance for the design of treatments for helminth infections, allergies and autoimmunity. Little is yet known regarding the co-stimulat...

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Detalles Bibliográficos
Autores principales: Redpath, Stephen A, van der Werf, Nienke, Cervera, Ana M, MacDonald, Andrew S, Gray, David, Maizels, Rick M, Taylor, Matthew D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615169/
https://www.ncbi.nlm.nih.gov/pubmed/23319295
http://dx.doi.org/10.1002/eji.201242794