Genome sequence of Staphylococcus lugdunensis N920143 allows identification of putative colonization and virulence factors

Staphylococcus lugdunensis is an opportunistic pathogen related to Staphylococcus aureus and Staphylococcus epidermidis. The genome sequence of S. lugdunensis strain N920143 has been compared with other staphylococci, and genes were identified that could promote survival of S. lugdunensis on human s...

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Detalles Bibliográficos
Autores principales: Heilbronner, Simon, Holden, Matthew TG, van Tonder, Andries, Geoghegan, Joan A, Foster, Timothy J, Parkhill, Julian, Bentley, Stephen D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Research Letters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615170/
https://www.ncbi.nlm.nih.gov/pubmed/21682763
http://dx.doi.org/10.1111/j.1574-6968.2011.02339.x
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author Heilbronner, Simon
Holden, Matthew TG
van Tonder, Andries
Geoghegan, Joan A
Foster, Timothy J
Parkhill, Julian
Bentley, Stephen D
author_facet Heilbronner, Simon
Holden, Matthew TG
van Tonder, Andries
Geoghegan, Joan A
Foster, Timothy J
Parkhill, Julian
Bentley, Stephen D
author_sort Heilbronner, Simon
collection PubMed
description Staphylococcus lugdunensis is an opportunistic pathogen related to Staphylococcus aureus and Staphylococcus epidermidis. The genome sequence of S. lugdunensis strain N920143 has been compared with other staphylococci, and genes were identified that could promote survival of S. lugdunensis on human skin and pathogenesis of infections. Staphylococcus lugdunensis lacks virulence factors that characterize S. aureus and harbours a smaller number of genes encoding surface proteins. It is the only staphylococcal species other than S. aureus that possesses a locus encoding iron-regulated surface determinant (Isd) proteins involved in iron acquisition from haemoglobin.
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spelling pubmed-36151702013-04-04 Genome sequence of Staphylococcus lugdunensis N920143 allows identification of putative colonization and virulence factors Heilbronner, Simon Holden, Matthew TG van Tonder, Andries Geoghegan, Joan A Foster, Timothy J Parkhill, Julian Bentley, Stephen D FEMS Microbiol Lett Research Letters Staphylococcus lugdunensis is an opportunistic pathogen related to Staphylococcus aureus and Staphylococcus epidermidis. The genome sequence of S. lugdunensis strain N920143 has been compared with other staphylococci, and genes were identified that could promote survival of S. lugdunensis on human skin and pathogenesis of infections. Staphylococcus lugdunensis lacks virulence factors that characterize S. aureus and harbours a smaller number of genes encoding surface proteins. It is the only staphylococcal species other than S. aureus that possesses a locus encoding iron-regulated surface determinant (Isd) proteins involved in iron acquisition from haemoglobin. Blackwell Publishing Ltd 2011-09 2011-07-04 /pmc/articles/PMC3615170/ /pubmed/21682763 http://dx.doi.org/10.1111/j.1574-6968.2011.02339.x Text en © 2011 Federation of European Microbiological Societies. Published by Blackwell Publishing Ltd. All rights reserved http://creativecommons.org/licenses/by/2.5/ Re-use of this article is permitted in accordance with the Creative Commons Deed, Attribution 2.5, which does not permit commercial exploitation.
spellingShingle Research Letters
Heilbronner, Simon
Holden, Matthew TG
van Tonder, Andries
Geoghegan, Joan A
Foster, Timothy J
Parkhill, Julian
Bentley, Stephen D
Genome sequence of Staphylococcus lugdunensis N920143 allows identification of putative colonization and virulence factors
title Genome sequence of Staphylococcus lugdunensis N920143 allows identification of putative colonization and virulence factors
title_full Genome sequence of Staphylococcus lugdunensis N920143 allows identification of putative colonization and virulence factors
title_fullStr Genome sequence of Staphylococcus lugdunensis N920143 allows identification of putative colonization and virulence factors
title_full_unstemmed Genome sequence of Staphylococcus lugdunensis N920143 allows identification of putative colonization and virulence factors
title_short Genome sequence of Staphylococcus lugdunensis N920143 allows identification of putative colonization and virulence factors
title_sort genome sequence of staphylococcus lugdunensis n920143 allows identification of putative colonization and virulence factors
topic Research Letters
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615170/
https://www.ncbi.nlm.nih.gov/pubmed/21682763
http://dx.doi.org/10.1111/j.1574-6968.2011.02339.x
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