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Germline excision of transgenes in Aedes aegypti by homing endonucleases

Aedes (Ae.) aegypti is the primary vector for dengue viruses (serotypes1–4) and chikungunya virus. Homing endonucleases (HEs) are ancient selfish elements that catalyze double-stranded DNA breaks (DSB) in a highly specific manner. In this report, we show that the HEs Y2-I-AniI, I-CreI and I-SceI are...

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Detalles Bibliográficos
Autores principales:	Aryan, Azadeh, Anderson, Michelle A. E., Myles, Kevin M., Adelman, Zach N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615334/ https://www.ncbi.nlm.nih.gov/pubmed/23549343 http://dx.doi.org/10.1038/srep01603

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