Drug and Disease Model Resources: A Consortium to Create Standards and Tools to Enhance Model-Based Drug Development

Model-based drug development (MBDD) is accepted as a vital approach in understanding patients' drug-related benefit and risk by integrating quantitative information integration from diverse sources collected throughout drug development.(1) This perspective introduces the activities of the Drug...

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Detalles Bibliográficos
Autores principales: Harnisch, L, Matthews, I, Chard, J, Karlsson, M O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615532/
https://www.ncbi.nlm.nih.gov/pubmed/23887647
http://dx.doi.org/10.1038/psp.2013.10
Descripción
Sumario:Model-based drug development (MBDD) is accepted as a vital approach in understanding patients' drug-related benefit and risk by integrating quantitative information integration from diverse sources collected throughout drug development.(1) This perspective introduces the activities of the Drug and Disease Model Resources (DDMoRe) consortium, founded in 2011 through the Innovative Medicines Initiative Joint Undertaking (IMI-JU)(2) as a European public–private partnership to address a lack of common tools, languages, and standards for modeling and simulation (M&S) to improve model-based knowledge integration.

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