Drug and Disease Model Resources: A Consortium to Create Standards and Tools to Enhance Model-Based Drug Development

Model-based drug development (MBDD) is accepted as a vital approach in understanding patients' drug-related benefit and risk by integrating quantitative information integration from diverse sources collected throughout drug development.(1) This perspective introduces the activities of the Drug...

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Detalles Bibliográficos
Autores principales: Harnisch, L, Matthews, I, Chard, J, Karlsson, M O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615532/
https://www.ncbi.nlm.nih.gov/pubmed/23887647
http://dx.doi.org/10.1038/psp.2013.10
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author Harnisch, L
Matthews, I
Chard, J
Karlsson, M O
author_facet Harnisch, L
Matthews, I
Chard, J
Karlsson, M O
author_sort Harnisch, L
collection PubMed
description Model-based drug development (MBDD) is accepted as a vital approach in understanding patients' drug-related benefit and risk by integrating quantitative information integration from diverse sources collected throughout drug development.(1) This perspective introduces the activities of the Drug and Disease Model Resources (DDMoRe) consortium, founded in 2011 through the Innovative Medicines Initiative Joint Undertaking (IMI-JU)(2) as a European public–private partnership to address a lack of common tools, languages, and standards for modeling and simulation (M&S) to improve model-based knowledge integration.
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spelling pubmed-36155322013-04-09 Drug and Disease Model Resources: A Consortium to Create Standards and Tools to Enhance Model-Based Drug Development Harnisch, L Matthews, I Chard, J Karlsson, M O CPT Pharmacometrics Syst Pharmacol Perspective Model-based drug development (MBDD) is accepted as a vital approach in understanding patients' drug-related benefit and risk by integrating quantitative information integration from diverse sources collected throughout drug development.(1) This perspective introduces the activities of the Drug and Disease Model Resources (DDMoRe) consortium, founded in 2011 through the Innovative Medicines Initiative Joint Undertaking (IMI-JU)(2) as a European public–private partnership to address a lack of common tools, languages, and standards for modeling and simulation (M&S) to improve model-based knowledge integration. Nature Publishing Group 2013-03 2013-03-20 /pmc/articles/PMC3615532/ /pubmed/23887647 http://dx.doi.org/10.1038/psp.2013.10 Text en Copyright © 2013 American Society for Clinical Pharmacology and Therapeutics http://creativecommons.org/licenses/by-nc-nd/3.0/ CPT: Pharmacometrics and Systems Pharmacology is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/
spellingShingle Perspective
Harnisch, L
Matthews, I
Chard, J
Karlsson, M O
Drug and Disease Model Resources: A Consortium to Create Standards and Tools to Enhance Model-Based Drug Development
title Drug and Disease Model Resources: A Consortium to Create Standards and Tools to Enhance Model-Based Drug Development
title_full Drug and Disease Model Resources: A Consortium to Create Standards and Tools to Enhance Model-Based Drug Development
title_fullStr Drug and Disease Model Resources: A Consortium to Create Standards and Tools to Enhance Model-Based Drug Development
title_full_unstemmed Drug and Disease Model Resources: A Consortium to Create Standards and Tools to Enhance Model-Based Drug Development
title_short Drug and Disease Model Resources: A Consortium to Create Standards and Tools to Enhance Model-Based Drug Development
title_sort drug and disease model resources: a consortium to create standards and tools to enhance model-based drug development
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615532/
https://www.ncbi.nlm.nih.gov/pubmed/23887647
http://dx.doi.org/10.1038/psp.2013.10
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