Cargando…

HTR8/SVneo Cells Display Trophoblast Progenitor Cell-Like Characteristics Indicative of Self-Renewal, Repopulation Activity, and Expression of “Stemness-” Associated Transcription Factors

Introduction. JEG3 is a choriocarcinoma—and HTR8/SVneo a transformed extravillous trophoblast—cell line often used to model the physiologically invasive extravillous trophoblast. Past studies suggest that these cell lines possess some stem or progenitor cell characteristics. Aim was to study whether...

Descripción completa

Detalles Bibliográficos
Autores principales:	Weber, Maja, Knoefler, Ilka, Schleussner, Ekkehard, Markert, Udo R., Fitzgerald, Justine S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615586/ https://www.ncbi.nlm.nih.gov/pubmed/23586024 http://dx.doi.org/10.1155/2013/243649

Ejemplares similares

Serum depletion induces changes in protein expression in the trophoblast-derived cell line HTR-8/SVneo
por: Novoa-Herran, Susana, et al.
Publicado: (2016)

AP-1 Transcription Factors, Mucin-Type Molecules and MMPs Regulate the IL-11 Mediated Invasiveness of JEG-3 and HTR-8/SVneo Trophoblastic Cells
por: Suman, Pankaj, et al.
Publicado: (2012)

Hepatocyte growth factor regulates HLX1 gene expression to modulate HTR-8/SVneo trophoblast cells
por: Liu, Hai-Ying, et al.
Publicado: (2012)

GABA A receptor π subunit promotes apoptosis of HTR-8/SVneo trophoblastic cells: Implications in preeclampsia
por: LU, JUNJIE, et al.
Publicado: (2016)

BMP9 maintains the phenotype of HTR-8/Svneo trophoblast cells by activating the SDF1/CXCR4 pathway
por: Yang, Xue, et al.
Publicado: (2023)

Isolation and Characterization of Human Trophoblast Side-Population (SP) Cells in Primary Villous Cytotrophoblasts and HTR-8/SVneo Cell Line
por: Takao, Tomoka, et al.
Publicado: (2011)

Delta-9-tetrahydrocannabinol inhibits invasion of HTR8/SVneo human extravillous trophoblast cells and negatively impacts mitochondrial function
por: Walker, O’Llenecia S., et al.
Publicado: (2021)

Lycium barbarum polysaccharides protect human trophoblast HTR8/SVneo cells from hydrogen peroxide-induced oxidative stress and apoptosis
por: Li, Jing, et al.
Publicado: (2018)

Valproate, thalidomide and ethyl alcohol alter the migration of HTR-8/SVneo cells
por: Rout, Ujjwal K
Publicado: (2006)

Psoralen Promotes Proliferation, Migration, and Invasion of Human Extravillous Trophoblast Derived HTR-8/Svneo Cells in vitro by NF-κB Pathway
por: Qi, Dan, et al.
Publicado: (2022)

Reduction in CgA-Derived CST Protein Level in HTR-8/SVneo and BeWo Trophoblastic Cell Lines Caused by the Preeclamptic Environment
por: Bralewska, Michalina, et al.
Publicado: (2023)

Exposure to environmental bisphenol A inhibits HTR-8/SVneo cell migration and invasion
por: Wei, Pu, et al.
Publicado: (2020)

Metabolic disparities of different oxidative stress-inducing conditions in HTR8/SVneo cells
por: Chen, Jingdong, et al.
Publicado: (2020)

miR-183-5p suppressed the invasion and migration of HTR-8/SVneo trophoblast cells partly via targeting MMP-9 in preeclampsia
por: Suo, Mingli, et al.
Publicado: (2020)

miR-17-5p Promotes Glucose Uptake of HTR8/SVneo Trophoblast Cells by Inhibiting TXNIP/NLRP3 Inflammasome Pathway
por: Jiang, Yi, et al.
Publicado: (2022)

MicroRNA-524-5p regulates the proliferation and invasion of HTR-8/SVneo trophoblasts by targeting NUMB in the Notch signaling pathway
por: Zheng, Linmei, et al.
Publicado: (2021)

Blocking Epidermal Growth Factor Receptor Signaling in HTR-8/SVneo First Trimester Trophoblast Cells Results in Dephosphorylation of PKBα/AKT and Induces Apoptosis
por: Bolnick, J., et al.
Publicado: (2011)

Reactive Oxygen Stimulation of Interleukin-6 Release in the Human Trophoblast Cell Line HTR-8/SVneo by the Trichlorethylene Metabolite S-(1,2-Dichloro)-l-Cysteine
por: Hassan, Iman, et al.
Publicado: (2016)

The Preeclamptic Environment Promotes the Activation of Transcription Factor Kappa B by P53/RSK1 Complex in a HTR8/SVneo Trophoblastic Cell Line
por: Sakowicz, Agata, et al.
Publicado: (2021)

Hyperin promotes proliferation, migration, and invasion of HTR-8/SVneo trophoblast cells via activation of JAK1/STAT3 pathway in recurrent spontaneous abortions
por: Mu, Zhenni, et al.
Publicado: (2023)

Autophagy in the HTR-8/SVneo Cell Oxidative Stress Model Is Associated with the NLRP1 Inflammasome
por: Li, Meihe, et al.
Publicado: (2021)

A Small Physiological Electric Field Mediated Responses of Extravillous Trophoblasts Derived from HTR8/SVneo Cells: Involvement of Activation of Focal Adhesion Kinase Signaling
por: Zhang, Juan, et al.
Publicado: (2014)

Increased Toxoplasma gondii Intracellular Proliferation in Human Extravillous Trophoblast Cells (HTR8/SVneo Line) Is Sequentially Triggered by MIF, ERK1/2, and COX-2
por: Milian, Iliana Claudia Balga, et al.
Publicado: (2019)

Curcumin Protects Human Trophoblast HTR8/SVneo Cells from H(2)O(2)-Induced Oxidative Stress by Activating Nrf2 Signaling Pathway
por: Qi, Lina, et al.
Publicado: (2020)

circRNA circ_0055724 Inhibits Trophoblastic Cell Line HTR-8/SVneo's Invasive and Migratory Abilities via the miR-136/N-Cadherin Axis
por: Xu, Xiaohong, et al.
Publicado: (2022)

Small GTP‐binding protein Rap1 mediates EGF and HB‐EGF signaling and modulates EGF receptor expression in HTR‐8/SVneo extravillous trophoblast cells
por: Yoshie, Mikihiro, et al.
Publicado: (2023)

Effects of transforming growth factor-β1 on the proliferation and invasion of the HTR-8/SVneo cell line
por: ZUO, YANZHEN, et al.
Publicado: (2014)

Hydrogen sulfide against preeclampsia exposure-induced oxidative mitochondrial damage in HTR-8/SVneo cells
por: Wang, Xianli, et al.
Publicado: (2022)

IGFBP-4 and −5 are expressed in first-trimester villi and differentially regulate the migration of HTR-8/SVneo cells
por: Crosley, Erin J, et al.
Publicado: (2014)

Interdependence of JAK-STAT and MAPK signaling pathways during EGF-mediated HTR-8/SVneo cell invasion
por: Malik, Ankita, et al.
Publicado: (2017)

Adenosine A(3) Receptor Mediates ERK1/2- and JNK-Dependent TNF-α Production in Toxoplasma gondii-Infected HTR8/SVneo Human Extravillous Trophoblast Cells
por: Ye, Wei, et al.
Publicado: (2020)

Nitroxide—HMP—Protects Human Trophoblast HTR-8/SVneo Cells from H(2)O(2)-Induced Oxidative Stress by Reducing the HIF1A Signaling Pathway
por: Pintye, Diana, et al.
Publicado: (2023)

Intranuclear Crosstalk between Extracellular Regulated Kinase1/2 and Signal Transducer and Activator of Transcription 3 Regulates JEG-3 Choriocarcinoma Cell Invasion and Proliferation
por: Morales-Prieto, Diana M., et al.
Publicado: (2013)

Bidirectional regulation between 1st trimester HTR8/SVneo trophoblast cells and in vitro differentiated Th17/Treg cells suggest a fetal‐maternal regulatory loop in human pregnancy
por: Wang, Songcun, et al.
Publicado: (2019)

Upregulated unique long 16 binding protein 1 detected in preeclamptic placenta affects human extravillous trophoblast cell line (HTR-8/SVneo) invasion by modulating the function of uterine natural killer cells
por: Liu, Jing, et al.
Publicado: (2017)

CTGF expression is up-regulated by PROK1 in early pregnancy and influences HTR-8/Svneo cell adhesion and network formation
por: Waddell, Jennifer M., et al.
Publicado: (2011)

MiR-519d-3p in Trophoblastic Cells: Effects, Targets and Transfer to Allogeneic Immune Cells via Extracellular Vesicles
por: Chaiwangyen, Wittaya, et al.
Publicado: (2020)

HOXD8/DIAPH2-AS1 epigenetically regulates PAX3 and impairs HTR-8/SVneo cell function under hypoxia
por: Feng, Yaling, et al.
Publicado: (2019)

Identification of LncRNA-miRNA-mRNA ceRNA network in hypoxia-induced HTR-8/SVneo cells for preeclampsia
por: Liu, Zhenzhen, et al.
Publicado: (2023)

Oncostatin M stimulates cell migration and proliferation by down-regulating E-cadherin in HTR8/SVneo cell line through STAT3 activation
por: Ko, Hyun Sun, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_drlpn64fqs40966j180t9899mk