Acute Generalized Exanthematous Pustulosis Induced by Etanercept: Another Dermatologic Adverse Effect

Acute generalized exanthematous pustulosis (AGEP) is a skin eruption that is primarily drug induced and characterized by the formation of numerous acute and sterile pustules on an erythematous background as mentioned by Weinblatt et al. (1999). We present a case of AGEP, following administration of...

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Detalles Bibliográficos
Autores principales: Kavala, Mukaddes, Zindancı, Ilkin, Türkoglu, Zafer, Can, Burçe, Kocatürk, Emek, Senol, Serkan, Topaloglu, Filiz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615587/
https://www.ncbi.nlm.nih.gov/pubmed/23573431
http://dx.doi.org/10.1155/2013/601412
Descripción
Sumario:Acute generalized exanthematous pustulosis (AGEP) is a skin eruption that is primarily drug induced and characterized by the formation of numerous acute and sterile pustules on an erythematous background as mentioned by Weinblatt et al. (1999). We present a case of AGEP, following administration of etanercept, an antitumour necrosis factor alpha (TNF-α) antibody, in a patient with psoriasis. Recognition of this reaction pattern is important given the frequent reliance on etanercept in treating psoriasis.

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