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Nanodomain Ca(2+) of Ca(2+) channels detected by a tethered genetically encoded Ca(2+) sensor

Coupling of excitation to secretion, contraction, and transcription often relies upon Ca(2+) computations within the nanodomain—a conceptual region extending tens of nanometers from the cytoplasmic mouth of Ca(2+) channels. Theory predicts that nanodomain Ca(2+) signals differ vastly from the slow s...

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Detalles Bibliográficos
Autores principales: Tay, Lai Hock, Dick, Ivy E., Yang, Wanjun, Mank, Marco, Griesbeck, Oliver, Yue, David T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615648/
https://www.ncbi.nlm.nih.gov/pubmed/22491326
http://dx.doi.org/10.1038/ncomms1777