Influenza A virus nucleoprotein induces apoptosis in human airway epithelial cells: implications of a novel interaction between nucleoprotein and host protein Clusterin

Apoptosis induction is an antiviral host response, however, influenza A virus (IAV) infection promotes host cell death. The nucleoprotein (NP) of IAV is known to contribute to viral pathogenesis, but its role in virus-induced host cell death was hitherto unknown. We observed that NP contributes to I...

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Detalles Bibliográficos
Autores principales: Tripathi, S, Batra, J, Cao, W, Sharma, K, Patel, J R, Ranjan, P, Kumar, A, Katz, J M, Cox, N J, Lal, R B, Sambhara, S, Lal, S K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615740/
https://www.ncbi.nlm.nih.gov/pubmed/23538443
http://dx.doi.org/10.1038/cddis.2013.89

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