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Influence of microRNA deregulation on chaperone-mediated autophagy and α-synuclein pathology in Parkinson's disease

The presence of α-synuclein aggregates in the characteristic Lewy body pathology seen in idiopathic Parkinson's disease (PD), together with α-synuclein gene mutations in familial PD, places α-synuclein at the center of PD pathogenesis. Decreased levels of the chaperone-mediated autophagy (CMA)...

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Detalles Bibliográficos
Autores principales:	Alvarez-Erviti, L, Seow, Y, Schapira, A HV, Rodriguez-Oroz, M C, Obeso, J A, Cooper, J M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615743/ https://www.ncbi.nlm.nih.gov/pubmed/23492776 http://dx.doi.org/10.1038/cddis.2013.73

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