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NMDA receptor regulation of levodopa-induced behavior and changes in striatal G protein-coupled receptor kinase 6 and â-arrestin-1 expression in parkinsonian rats

BACKGROUND: Parkinson’s disease is a neurodegenerative disorder caused by loss of dopaminergic neurons in the substantia nigra. The dopamine precursor, levodopa, remains the most effective and common treatment for this disorder. However, long-term administration of levodopa is known to induce charac...

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Detalles Bibliográficos
Autores principales: Wu, Na, Song, Lu, Yang, Xinxin, Yuan, Weien, Liu, Zhenguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615843/
https://www.ncbi.nlm.nih.gov/pubmed/23569367
http://dx.doi.org/10.2147/CIA.S41464