Cargando…
NMDA receptor regulation of levodopa-induced behavior and changes in striatal G protein-coupled receptor kinase 6 and â-arrestin-1 expression in parkinsonian rats
BACKGROUND: Parkinson’s disease is a neurodegenerative disorder caused by loss of dopaminergic neurons in the substantia nigra. The dopamine precursor, levodopa, remains the most effective and common treatment for this disorder. However, long-term administration of levodopa is known to induce charac...
Autores principales: | Wu, Na, Song, Lu, Yang, Xinxin, Yuan, Weien, Liu, Zhenguo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615843/ https://www.ncbi.nlm.nih.gov/pubmed/23569367 http://dx.doi.org/10.2147/CIA.S41464 |
Ejemplares similares
-
Effect of Tianqi antitremor granules on behavioral manifestations and expression of G protein-coupled receptor kinase 6 and β-arrestin1 in levodopa-induced dyskinesia in a rat model of Parkinson’s disease
por: Wu, Na, et al.
Publicado: (2013) -
Levodopa/benserazide microspheres reduced levodopa-induced dyskinesia by downregulating phosphorylated GluR1 expression in 6-OHDA-lesioned rats
por: Yang, Xinxin, et al.
Publicado: (2012) -
G protein–receptor kinases 5/6 are the key regulators of G protein–coupled receptor 35–arrestin interactions
por: Ganguly, Amlan, et al.
Publicado: (2023) -
Controlled-release levodopa methyl ester/benserazide-loaded nanoparticles ameliorate levodopa-induced dyskinesia in rats
por: Yang, Xinxin, et al.
Publicado: (2012) -
Competing G protein-coupled receptor kinases balance G protein and β-arrestin signaling
por: Heitzler, Domitille, et al.
Publicado: (2012)