Development of primary malignant melanoma during treatment with a TNF-α antagonist for severe Crohn’s disease: a case report and review of the hypothetical association between TNF-α blockers and cancer

It is recognized that immunosuppression may lead to reduced immune surveillance and tumor formation. Because of the immunosuppressive properties of tumor necrosis factor (TNF)-alpha (TNF-α) antagonists, it is plausible that these biologics may increase the risk of the occurrence of malignancies or t...

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Detalles Bibliográficos
Autores principales: Kouklakis, George, Efremidou, Eleni I, Pitiakoudis, Michael, Liratzopoulos, Nikolaos, Polychronidis, Alexandros Ch
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615922/
https://www.ncbi.nlm.nih.gov/pubmed/23569358
http://dx.doi.org/10.2147/DDDT.S41889

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