A novel dendritic nanocarrier of polyamidoamine-polyethylene glycol-cyclic RGD for “smart” small interfering RNA delivery and in vitro antitumor effects by human ether-à-go-go-related gene silencing in anaplastic thyroid carcinoma cells

The application of RNA interference techniques is promising in gene therapeutic approaches, especially for cancers. To improve safety and efficiency of small interfering RNA (siRNA) delivery, a triblock dendritic nanocarrier, polyamidoamine-polyethylene glycol-cyclic RGD (PAMAM-PEG-cRGD), was develo...

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Detalles Bibliográficos
Autores principales: Li, Guanhua, Hu, Zuojun, Yin, Henghui, Zhang, Yunjian, Huang, Xueling, Wang, Shenming, Li, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615931/
https://www.ncbi.nlm.nih.gov/pubmed/23569377
http://dx.doi.org/10.2147/IJN.S41555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615931/
https://www.ncbi.nlm.nih.gov/pubmed/23569377
http://dx.doi.org/10.2147/IJN.S41555

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