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Oral bioavailability of cantharidin-loaded solid lipid nanoparticles
BACKGROUND: The clinical application of cantharidin (CA) is limited by its insolubility, toxicity and short half-life in circulation. This study aims to achieve a steady and sustained blood concentration–time profile, using solid lipid nanoparticles (SLNs) as a drug carrier. METHODS: CA-SLNs were pr...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615953/ https://www.ncbi.nlm.nih.gov/pubmed/23298453 http://dx.doi.org/10.1186/1749-8546-8-1 |