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HDAC6 as a target for neurodegenerative diseases: what makes it different from the other HDACs?
Histone deacetylase (HDAC) inhibitors have been demonstrated to be beneficial in animal models of neurodegenerative diseases. Such results were mainly associated with the epigenetic modulation caused by HDACs, especially those from class I, via chromatin deacetylation. However, other mechanisms may...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615964/ https://www.ncbi.nlm.nih.gov/pubmed/23356410 http://dx.doi.org/10.1186/1750-1326-8-7 |