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Primary anorectal melanoma: A case report with extended follow-up

BACKGROUND: Anorectal melanoma is a rare and aggressive disease. The mainstay of treatment is usually surgical with curative or palliative intent, since radio- and chemotherapy do not really improve the outcome. The poor prognosis is attributable to delay in diagnosis and its inherent biologic aggre...

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Autores principales: Lagha, Aymen, Ayadi, Mouna, Krimi, Sarra, Chraiet, Nesrine, Allani, Bassem, Rifi, Hela, Raies, Henda, Mezlini, Amel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615979/
https://www.ncbi.nlm.nih.gov/pubmed/23569542
http://dx.doi.org/10.12659/AJCR.883506
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author Lagha, Aymen
Ayadi, Mouna
Krimi, Sarra
Chraiet, Nesrine
Allani, Bassem
Rifi, Hela
Raies, Henda
Mezlini, Amel
author_facet Lagha, Aymen
Ayadi, Mouna
Krimi, Sarra
Chraiet, Nesrine
Allani, Bassem
Rifi, Hela
Raies, Henda
Mezlini, Amel
author_sort Lagha, Aymen
collection PubMed
description BACKGROUND: Anorectal melanoma is a rare and aggressive disease. The mainstay of treatment is usually surgical with curative or palliative intent, since radio- and chemotherapy do not really improve the outcome. The poor prognosis is attributable to delay in diagnosis and its inherent biologic aggressiveness. CASE REPORT: We present a case of anorectal melanoma in a 68-year-old man who underwent solely abdominoperineal amputation and was doing well 30 months after surgery, without any evidence of recurrent disease. CONCLUSIONS: Treatment of anorectal melanoma should be by the least morbid means possible. Surgical procedure that can achieve a complete local excision and respect the functional aspects and quality of life of the patient remains the best therapeutic approach. No systemic regimen for metastatic anorectal melanoma is considered standard of care.
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spelling pubmed-36159792013-04-08 Primary anorectal melanoma: A case report with extended follow-up Lagha, Aymen Ayadi, Mouna Krimi, Sarra Chraiet, Nesrine Allani, Bassem Rifi, Hela Raies, Henda Mezlini, Amel Am J Case Rep Case Report BACKGROUND: Anorectal melanoma is a rare and aggressive disease. The mainstay of treatment is usually surgical with curative or palliative intent, since radio- and chemotherapy do not really improve the outcome. The poor prognosis is attributable to delay in diagnosis and its inherent biologic aggressiveness. CASE REPORT: We present a case of anorectal melanoma in a 68-year-old man who underwent solely abdominoperineal amputation and was doing well 30 months after surgery, without any evidence of recurrent disease. CONCLUSIONS: Treatment of anorectal melanoma should be by the least morbid means possible. Surgical procedure that can achieve a complete local excision and respect the functional aspects and quality of life of the patient remains the best therapeutic approach. No systemic regimen for metastatic anorectal melanoma is considered standard of care. International Scientific Literature, Inc. 2012-10-15 /pmc/articles/PMC3615979/ /pubmed/23569542 http://dx.doi.org/10.12659/AJCR.883506 Text en © Am J Case Rep, 2012 This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License.
spellingShingle Case Report
Lagha, Aymen
Ayadi, Mouna
Krimi, Sarra
Chraiet, Nesrine
Allani, Bassem
Rifi, Hela
Raies, Henda
Mezlini, Amel
Primary anorectal melanoma: A case report with extended follow-up
title Primary anorectal melanoma: A case report with extended follow-up
title_full Primary anorectal melanoma: A case report with extended follow-up
title_fullStr Primary anorectal melanoma: A case report with extended follow-up
title_full_unstemmed Primary anorectal melanoma: A case report with extended follow-up
title_short Primary anorectal melanoma: A case report with extended follow-up
title_sort primary anorectal melanoma: a case report with extended follow-up
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615979/
https://www.ncbi.nlm.nih.gov/pubmed/23569542
http://dx.doi.org/10.12659/AJCR.883506
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