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Primary anorectal melanoma: A case report with extended follow-up
BACKGROUND: Anorectal melanoma is a rare and aggressive disease. The mainstay of treatment is usually surgical with curative or palliative intent, since radio- and chemotherapy do not really improve the outcome. The poor prognosis is attributable to delay in diagnosis and its inherent biologic aggre...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615979/ https://www.ncbi.nlm.nih.gov/pubmed/23569542 http://dx.doi.org/10.12659/AJCR.883506 |
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author | Lagha, Aymen Ayadi, Mouna Krimi, Sarra Chraiet, Nesrine Allani, Bassem Rifi, Hela Raies, Henda Mezlini, Amel |
author_facet | Lagha, Aymen Ayadi, Mouna Krimi, Sarra Chraiet, Nesrine Allani, Bassem Rifi, Hela Raies, Henda Mezlini, Amel |
author_sort | Lagha, Aymen |
collection | PubMed |
description | BACKGROUND: Anorectal melanoma is a rare and aggressive disease. The mainstay of treatment is usually surgical with curative or palliative intent, since radio- and chemotherapy do not really improve the outcome. The poor prognosis is attributable to delay in diagnosis and its inherent biologic aggressiveness. CASE REPORT: We present a case of anorectal melanoma in a 68-year-old man who underwent solely abdominoperineal amputation and was doing well 30 months after surgery, without any evidence of recurrent disease. CONCLUSIONS: Treatment of anorectal melanoma should be by the least morbid means possible. Surgical procedure that can achieve a complete local excision and respect the functional aspects and quality of life of the patient remains the best therapeutic approach. No systemic regimen for metastatic anorectal melanoma is considered standard of care. |
format | Online Article Text |
id | pubmed-3615979 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | International Scientific Literature, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-36159792013-04-08 Primary anorectal melanoma: A case report with extended follow-up Lagha, Aymen Ayadi, Mouna Krimi, Sarra Chraiet, Nesrine Allani, Bassem Rifi, Hela Raies, Henda Mezlini, Amel Am J Case Rep Case Report BACKGROUND: Anorectal melanoma is a rare and aggressive disease. The mainstay of treatment is usually surgical with curative or palliative intent, since radio- and chemotherapy do not really improve the outcome. The poor prognosis is attributable to delay in diagnosis and its inherent biologic aggressiveness. CASE REPORT: We present a case of anorectal melanoma in a 68-year-old man who underwent solely abdominoperineal amputation and was doing well 30 months after surgery, without any evidence of recurrent disease. CONCLUSIONS: Treatment of anorectal melanoma should be by the least morbid means possible. Surgical procedure that can achieve a complete local excision and respect the functional aspects and quality of life of the patient remains the best therapeutic approach. No systemic regimen for metastatic anorectal melanoma is considered standard of care. International Scientific Literature, Inc. 2012-10-15 /pmc/articles/PMC3615979/ /pubmed/23569542 http://dx.doi.org/10.12659/AJCR.883506 Text en © Am J Case Rep, 2012 This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. |
spellingShingle | Case Report Lagha, Aymen Ayadi, Mouna Krimi, Sarra Chraiet, Nesrine Allani, Bassem Rifi, Hela Raies, Henda Mezlini, Amel Primary anorectal melanoma: A case report with extended follow-up |
title | Primary anorectal melanoma: A case report with extended follow-up |
title_full | Primary anorectal melanoma: A case report with extended follow-up |
title_fullStr | Primary anorectal melanoma: A case report with extended follow-up |
title_full_unstemmed | Primary anorectal melanoma: A case report with extended follow-up |
title_short | Primary anorectal melanoma: A case report with extended follow-up |
title_sort | primary anorectal melanoma: a case report with extended follow-up |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615979/ https://www.ncbi.nlm.nih.gov/pubmed/23569542 http://dx.doi.org/10.12659/AJCR.883506 |
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