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An Empirical Evaluation of Normalization Methods for MicroRNA Arrays in a Liposarcoma Study
BACKGROUND: Methods for array normalization, such as median and quantile normalization, were developed for mRNA expression arrays. These methods assume few or symmetric differential expression of genes on the array. However, these assumptions are not necessarily appropriate for microRNA expression a...
Autores principales: | Qin, Li-Xuan, Tuschl, Tom, Singer, Samuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3615992/ https://www.ncbi.nlm.nih.gov/pubmed/23589668 http://dx.doi.org/10.4137/CIN.S11384 |
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