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Kras Gene Mutation and RASSF1A, FHIT and MGMT Gene Promoter Hypermethylation: Indicators of Tumor Staging and Metastasis in Adenocarcinomatous Sporadic Colorectal Cancer in Indian Population
OBJECTIVE: Colorectal cancer (CRC) development involves underlying modifications at genetic/epigenetic level. This study evaluated the role of Kras gene mutation and RASSF1A, FHIT and MGMT gene promoter hypermethylation together/independently in sporadic CRC in Indian population and correlation with...
Autores principales: | Sinha, Rupal, Hussain, Showket, Mehrotra, Ravi, Kumar, R. Suresh, Kumar, Kapil, Pande, Pankaj, Doval, Dinesh Chandra, Basir, Seemi Farhat, Bharadwaj, Mausumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616004/ https://www.ncbi.nlm.nih.gov/pubmed/23573237 http://dx.doi.org/10.1371/journal.pone.0060142 |
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