Multiple active centers of multi-subunit RNA polymerases

The active center of multi-subunit RNA polymerase consists of two modules, the Mg(2+) module, holding the catalytic Mg(2+) ion, and a module made of a flexible domain, the Trigger Loop. Uniquely, the “TL module” can be substituted by “alternative modules,” thus changing the catalytic properties of t...

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Detalles Bibliográficos
Autores principales: Yuzenkova, Yulia, Roghanian, Mohammad, Zenkin, Nikolay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Point of View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616080/
https://www.ncbi.nlm.nih.gov/pubmed/22771945
http://dx.doi.org/10.4161/trns.19887
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author Yuzenkova, Yulia
Roghanian, Mohammad
Zenkin, Nikolay
author_facet Yuzenkova, Yulia
Roghanian, Mohammad
Zenkin, Nikolay
author_sort Yuzenkova, Yulia
collection PubMed
description The active center of multi-subunit RNA polymerase consists of two modules, the Mg(2+) module, holding the catalytic Mg(2+) ion, and a module made of a flexible domain, the Trigger Loop. Uniquely, the “TL module” can be substituted by “alternative modules,” thus changing the catalytic properties of the active center.
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spelling pubmed-36160802013-04-22 Multiple active centers of multi-subunit RNA polymerases Yuzenkova, Yulia Roghanian, Mohammad Zenkin, Nikolay Transcription Point of View The active center of multi-subunit RNA polymerase consists of two modules, the Mg(2+) module, holding the catalytic Mg(2+) ion, and a module made of a flexible domain, the Trigger Loop. Uniquely, the “TL module” can be substituted by “alternative modules,” thus changing the catalytic properties of the active center. Landes Bioscience 2012-05-01 /pmc/articles/PMC3616080/ /pubmed/22771945 http://dx.doi.org/10.4161/trns.19887 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Point of View
Yuzenkova, Yulia
Roghanian, Mohammad
Zenkin, Nikolay
Multiple active centers of multi-subunit RNA polymerases
title Multiple active centers of multi-subunit RNA polymerases
title_full Multiple active centers of multi-subunit RNA polymerases
title_fullStr Multiple active centers of multi-subunit RNA polymerases
title_full_unstemmed Multiple active centers of multi-subunit RNA polymerases
title_short Multiple active centers of multi-subunit RNA polymerases
title_sort multiple active centers of multi-subunit rna polymerases
topic Point of View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616080/
https://www.ncbi.nlm.nih.gov/pubmed/22771945
http://dx.doi.org/10.4161/trns.19887
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