Cargando…
Structural and Phylogenetic Studies with MjTX-I Reveal a Multi-Oligomeric Toxin – a Novel Feature in Lys49-PLA(2)s Protein Class
The mortality caused by snakebites is more damaging than many tropical diseases, such as dengue haemorrhagic fever, cholera, leishmaniasis, schistosomiasis and Chagas disease. For this reason, snakebite envenoming adversely affects health services of tropical and subtropical countries and is recogni...
Autores principales: | Salvador, Guilherme H. M., Fernandes, Carlos A. H., Magro, Angelo J., Marchi-Salvador, Daniela P., Cavalcante, Walter L. G., Fernandez, Roberto M., Gallacci, Márcia, Soares, Andreimar M., Oliveira, Cristiano L. P., Fontes, Marcos R. M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616104/ https://www.ncbi.nlm.nih.gov/pubmed/23573271 http://dx.doi.org/10.1371/journal.pone.0060610 |
Ejemplares similares
-
Structural and functional characterization of suramin-bound MjTX-I from Bothrops moojeni suggests a particular myotoxic mechanism
por: Salvador, Guilherme H. M., et al.
Publicado: (2018) -
Structural and Functional Studies of a Bothropic Myotoxin Complexed to Rosmarinic Acid: New Insights into Lys49-PLA(2) Inhibition
por: dos Santos, Juliana I., et al.
Publicado: (2011) -
Cytotoxic and pro-apoptotic action of MjTX-I, a phospholipase A2 isolated from Bothrops moojeni snake venom, towards leukemic cells
por: Benati, Rogério Bodini, et al.
Publicado: (2018) -
SDS-induced oligomerization of Lys49-phospholipase A(2) from snake venom
por: Matsui, Takashi, et al.
Publicado: (2019) -
Purification and Preliminary Crystallographic Analysis of a New Lys49-PLA2 from B. Jararacussu
por: dos Santos, Marcelo L., et al.
Publicado: (2008)