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Genetic Variations in SMAD7 Are Associated with Colorectal Cancer Risk in the Colon Cancer Family Registry

BACKGROUND: Recent genome-wide studies identified a risk locus for colorectal cancer at 18q21, which maps to the SMAD7 gene. Our objective was to confirm the association between SMAD7 SNPs and colorectal cancer risk in the multi-center Colon Cancer Family Registry. MATERIALS AND METHODS: 23 tagging...

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Detalles Bibliográficos
Autores principales:	Jiang, Xuejuan, Castelao, J. Esteban, Vandenberg, David, Carracedo, Angel, Redondo, Carmen M., Conti, David V., Paredes Cotoré, Jesus P., Potter, John D., Newcomb, Polly A., Passarelli, Michael N., Jenkins, Mark A., Hopper, John L., Gallinger, Steven, Le Marchand, Loic, Martínez, María E., Ahnen, Dennis J., Baron, John A., Lindor, Noralane M., Haile, Robert W., Gago-Dominguez, Manuela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616155/ https://www.ncbi.nlm.nih.gov/pubmed/23560096 http://dx.doi.org/10.1371/journal.pone.0060464

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