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Community-associated methicillin-resistant staphylococcus aureus epidemic clone USA100; more than a nosocomial pathogen

BACKGROUND: We characterized 100 USA100 epidemic MRSA from individuals in the community with no known healthcare-associated risk factors. FINDINGS: Molecular epidemiology demonstrated 21 pulsed-field types and six spa types. SCCmec typing demonstrated that all of the strains possess the type II cass...

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Detalles Bibliográficos
Autor principal: Roberts, Jill C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing AG 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616214/
https://www.ncbi.nlm.nih.gov/pubmed/23565358
http://dx.doi.org/10.1186/2193-1801-2-133
Descripción
Sumario:BACKGROUND: We characterized 100 USA100 epidemic MRSA from individuals in the community with no known healthcare-associated risk factors. FINDINGS: Molecular epidemiology demonstrated 21 pulsed-field types and six spa types. SCCmec typing demonstrated that all of the strains possess the type II cassette. The staphylococcal enterotoxin D virulence gene was also present. CONCLUSION: Characterization of USA100 MRSA in the community illustrated the importance of nasal carriage, and the genetic diversity of the USA100 clone.