Age-associated alterations in inducible gene transcription in human CD4(+) T lymphocytes

Age associated immune dysregulation results in a pro-inflammatory state and increased susceptibility to infections and autoimmune diseases. Studies show that signaling initiated at the T cell antigen receptor (TCR) is impaired in CD4(+) T cells from old compared to young mice. Here we examined TCR-i...

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Detalles Bibliográficos
Autores principales: Bektas, Arsun, Zhang, Yongqing, Wood, William H., Becker, Kevin G., Madara, Karen, Ferrucci, Luigi, Sen, Ranjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616229/
https://www.ncbi.nlm.nih.gov/pubmed/23385138

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