Specific lipofuscin staining as a novel biomarker to detect replicative and stress-induced senescence. A method applicable in cryo-preserved and archival tissues

There is shortage of extensive clinicopathologic studies of cellular senescence because the most reliable senescence biomarker, the detection of Senescence-Associated-beta-galactosidase activity (SA-β-gal), is inapplicable in archival material and requires snap-frozen tissues. We validated the histo...

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Detalles Bibliográficos
Autores principales: Georgakopoulou, EA, Tsimaratou, K, Evangelou, K, Fernandez, Marcos-PJ, Zoumpourlis, V, Trougakos, IP, Kletsas, D, Bartek, J, Serrano, M, Gorgoulis, VG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2012
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616230/
https://www.ncbi.nlm.nih.gov/pubmed/23449538

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