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Genome editing with RNA-guided Cas9 nuclease in Zebrafish embryos
Recent advances with the type II clustered regularly interspaced short palindromic repeats (CRISPR) system promise an improved approach to genome editing. However, the applicability and efficiency of this system in model organisms, such as zebrafish, are little studied. Here, we report that RNA-guid...
Autores principales: | Chang, Nannan, Sun, Changhong, Gao, Lu, Zhu, Dan, Xu, Xiufei, Zhu, Xiaojun, Xiong, Jing-Wei, Xi, Jianzhong Jeff |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616424/ https://www.ncbi.nlm.nih.gov/pubmed/23528705 http://dx.doi.org/10.1038/cr.2013.45 |
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