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Knockdown of cathepsin D in zebrafish fertilized eggs determines congenital myopathy
CD (cathepsin D) is a ubiquitous lysosomal hydrolase involved in a variety of pathophysiological functions, including protein turnover, activation of pro-hormones, cell death and embryo development. CD-mediated proteolysis plays a pivotal role in tissue and organ homoeostasis. Altered expression and...
Autores principales: | Follo, Carlo, Ozzano, Matteo, Montalenti, Claudia, Santoro, Massimo Mattia, Isidoro, Ciro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616520/ https://www.ncbi.nlm.nih.gov/pubmed/23464837 http://dx.doi.org/10.1042/BSR20120100 |
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