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Enhanced Intrapulmonary Delivery of Anticancer siRNA for Lung Cancer Therapy Using Cationic Ethylphosphocholine-based Nanolipoplexes
Here, we report a cationic nanolipoplex as a pulmonary cellular delivery system for small-interfering RNA (siRNA). Six nanoliposomes differing in cationic lipids were formulated and screened in vitro and in vivo for cellular delivery functions in lung cells/tissues. Although the six nanoliposomes sh...
Autores principales: | Shim, Gayong, Choi, Hyun-woo, Lee, Sangbin, Choi, Junhyeok, Yu, Yong Hee, Park, Da-Eui, Choi, Yongseok, Kim, Chan-Wha, Oh, Yu-Kyoung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616525/ https://www.ncbi.nlm.nih.gov/pubmed/23380818 http://dx.doi.org/10.1038/mt.2013.10 |
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