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Rescue of Impaired NK Cell Activity in Hodgkin Lymphoma With Bispecific Antibodies In Vitro and in Patients
Natural killer (NK) cells represent a key component of the innate immune system against cancer. Nevertheless, malignant diseases arise in immunocompetent individuals despite tumor immunosurveillance. Hodgkin lymphoma (HL) is characterized by CD30(+) tumor cells and a massive infiltration of immune e...
Autores principales: | Reiners, Katrin S., Kessler, Jörg, Sauer, Maike, Rothe, Achim, Hansen, Hinrich P., Reusch, Uwe, Hucke, Christian, Köhl, Ulrike, Dürkop, Horst, Engert, Andreas, von Strandmann, Elke Pogge |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616527/ https://www.ncbi.nlm.nih.gov/pubmed/23459515 http://dx.doi.org/10.1038/mt.2013.14 |
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