Cargando…

Hospital visits among women with skeletal-related events secondary to breast cancer and bone metastases: a nationwide population-based cohort study in Denmark

OBJECTIVE: Skeletal-related events (SREs) among women with breast cancer may be associated with considerable use of health-care resources. We characterized inpatient and outpatient hospital visits in a national population-based cohort of Danish women with SREs secondary to breast cancer and bone met...

Descripción completa

Detalles Bibliográficos
Autores principales: Svendsen, Marie Louise, Gammelager, Henrik, Sværke, Claus, Yong, Mellissa, Chia, Victoria M, Christiansen, Christian F, Fryzek, Jon P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616605/
https://www.ncbi.nlm.nih.gov/pubmed/23576882
http://dx.doi.org/10.2147/CLEP.S42325
_version_ 1782265150206640128
author Svendsen, Marie Louise
Gammelager, Henrik
Sværke, Claus
Yong, Mellissa
Chia, Victoria M
Christiansen, Christian F
Fryzek, Jon P
author_facet Svendsen, Marie Louise
Gammelager, Henrik
Sværke, Claus
Yong, Mellissa
Chia, Victoria M
Christiansen, Christian F
Fryzek, Jon P
author_sort Svendsen, Marie Louise
collection PubMed
description OBJECTIVE: Skeletal-related events (SREs) among women with breast cancer may be associated with considerable use of health-care resources. We characterized inpatient and outpatient hospital visits in a national population-based cohort of Danish women with SREs secondary to breast cancer and bone metastases. METHODS: We identified first-time breast cancer patients with bone metastases from 2003 through 2009 who had a subsequent SRE (defined as pathologic fracture, spinal cord compression, radiation therapy, or surgery to bone). Hospital visits included the number of inpatient hospitalizations, length of stay, number of hospital outpatient clinic visits, and emergency room visits. The number of hospital visits was assessed for a pre-SRE period (90 days prior to the diagnostic period), a diagnostic period (14 days prior to the SRE), and a post-SRE period (90 days after the SRE). Patients who experienced more than one SRE during the 90-day post-SRE period were defined as having multiple SREs and were followed until 90 days after the last SRE. RESULTS: We identified 569 women with SREs secondary to breast cancer with bone metastases. The majority of women had multiple SREs (73.1%). A total of 20.9% and 33.4% of women with single and multiple SREs died in the post-SRE period, respectively. SREs were associated with a large number of hospital visits in the diagnostic period, irrespective of the number and type of SREs. Women with multiple SREs generally had a higher number of visits compared to those with a single SRE in the post-SRE period, eg, median length of hospitalization was 5 days (interquartile range 0–15) for women with a single SRE and 13 days (interquartile range 4–30) for women with multiple SREs. CONCLUSION: SREs secondary to breast cancer and bone metastases were associated with substantial use of hospital resources.
format Online
Article
Text
id pubmed-3616605
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Dove Medical Press
record_format MEDLINE/PubMed
spelling pubmed-36166052013-04-10 Hospital visits among women with skeletal-related events secondary to breast cancer and bone metastases: a nationwide population-based cohort study in Denmark Svendsen, Marie Louise Gammelager, Henrik Sværke, Claus Yong, Mellissa Chia, Victoria M Christiansen, Christian F Fryzek, Jon P Clin Epidemiol Short Report OBJECTIVE: Skeletal-related events (SREs) among women with breast cancer may be associated with considerable use of health-care resources. We characterized inpatient and outpatient hospital visits in a national population-based cohort of Danish women with SREs secondary to breast cancer and bone metastases. METHODS: We identified first-time breast cancer patients with bone metastases from 2003 through 2009 who had a subsequent SRE (defined as pathologic fracture, spinal cord compression, radiation therapy, or surgery to bone). Hospital visits included the number of inpatient hospitalizations, length of stay, number of hospital outpatient clinic visits, and emergency room visits. The number of hospital visits was assessed for a pre-SRE period (90 days prior to the diagnostic period), a diagnostic period (14 days prior to the SRE), and a post-SRE period (90 days after the SRE). Patients who experienced more than one SRE during the 90-day post-SRE period were defined as having multiple SREs and were followed until 90 days after the last SRE. RESULTS: We identified 569 women with SREs secondary to breast cancer with bone metastases. The majority of women had multiple SREs (73.1%). A total of 20.9% and 33.4% of women with single and multiple SREs died in the post-SRE period, respectively. SREs were associated with a large number of hospital visits in the diagnostic period, irrespective of the number and type of SREs. Women with multiple SREs generally had a higher number of visits compared to those with a single SRE in the post-SRE period, eg, median length of hospitalization was 5 days (interquartile range 0–15) for women with a single SRE and 13 days (interquartile range 4–30) for women with multiple SREs. CONCLUSION: SREs secondary to breast cancer and bone metastases were associated with substantial use of hospital resources. Dove Medical Press 2013-03-26 /pmc/articles/PMC3616605/ /pubmed/23576882 http://dx.doi.org/10.2147/CLEP.S42325 Text en © 2013 Svendsen et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Short Report
Svendsen, Marie Louise
Gammelager, Henrik
Sværke, Claus
Yong, Mellissa
Chia, Victoria M
Christiansen, Christian F
Fryzek, Jon P
Hospital visits among women with skeletal-related events secondary to breast cancer and bone metastases: a nationwide population-based cohort study in Denmark
title Hospital visits among women with skeletal-related events secondary to breast cancer and bone metastases: a nationwide population-based cohort study in Denmark
title_full Hospital visits among women with skeletal-related events secondary to breast cancer and bone metastases: a nationwide population-based cohort study in Denmark
title_fullStr Hospital visits among women with skeletal-related events secondary to breast cancer and bone metastases: a nationwide population-based cohort study in Denmark
title_full_unstemmed Hospital visits among women with skeletal-related events secondary to breast cancer and bone metastases: a nationwide population-based cohort study in Denmark
title_short Hospital visits among women with skeletal-related events secondary to breast cancer and bone metastases: a nationwide population-based cohort study in Denmark
title_sort hospital visits among women with skeletal-related events secondary to breast cancer and bone metastases: a nationwide population-based cohort study in denmark
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616605/
https://www.ncbi.nlm.nih.gov/pubmed/23576882
http://dx.doi.org/10.2147/CLEP.S42325
work_keys_str_mv AT svendsenmarielouise hospitalvisitsamongwomenwithskeletalrelatedeventssecondarytobreastcancerandbonemetastasesanationwidepopulationbasedcohortstudyindenmark
AT gammelagerhenrik hospitalvisitsamongwomenwithskeletalrelatedeventssecondarytobreastcancerandbonemetastasesanationwidepopulationbasedcohortstudyindenmark
AT sværkeclaus hospitalvisitsamongwomenwithskeletalrelatedeventssecondarytobreastcancerandbonemetastasesanationwidepopulationbasedcohortstudyindenmark
AT yongmellissa hospitalvisitsamongwomenwithskeletalrelatedeventssecondarytobreastcancerandbonemetastasesanationwidepopulationbasedcohortstudyindenmark
AT chiavictoriam hospitalvisitsamongwomenwithskeletalrelatedeventssecondarytobreastcancerandbonemetastasesanationwidepopulationbasedcohortstudyindenmark
AT christiansenchristianf hospitalvisitsamongwomenwithskeletalrelatedeventssecondarytobreastcancerandbonemetastasesanationwidepopulationbasedcohortstudyindenmark
AT fryzekjonp hospitalvisitsamongwomenwithskeletalrelatedeventssecondarytobreastcancerandbonemetastasesanationwidepopulationbasedcohortstudyindenmark