Accelerated drug release and clearance of PEGylated epirubicin liposomes following repeated injections: a new challenge for sequential low-dose chemotherapy

BACKGROUND: Sequential low-dose chemotherapy has received great attention for its unique advantages in attenuating multidrug resistance of tumor cells. Nevertheless, it runs the risk of producing new problems associated with the accelerated blood clearance phenomenon, especially with multiple inject...

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Detalles Bibliográficos
Autores principales: Yang, Qiang, Ma, Yanling, Zhao, Yongxue, She, Zhennan, Wang, Long, Li, Jie, Wang, Chunling, Deng, Yihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616606/
https://www.ncbi.nlm.nih.gov/pubmed/23576868
http://dx.doi.org/10.2147/IJN.S41701

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