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Co-regulated expression of alpha and beta mRNAs encoding HLA-DR surface heterodimers is mediated by the MHCII RNA operon

Major histocompatibility complex class II (MHCII) molecules are heterodimeric surface proteins involved in the presentation of exogenous antigens during the adaptive immune response. We demonstrate the existence of a fine level of regulation, coupling the transcription and processing of mRNAs encodi...

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Detalles Bibliográficos
Autores principales: Pisapia, Laura, Cicatiello, Valeria, Barba, Pasquale, Malanga, Donatella, Maffei, Antonella, Hamilton, Russell S., Del Pozzo, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616700/
https://www.ncbi.nlm.nih.gov/pubmed/23393186
http://dx.doi.org/10.1093/nar/gkt059