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In-solution hybrid capture of bisulfite-converted DNA for targeted bisulfite sequencing of 174 ADME genes
DNA methylation is one of the most important epigenetic alterations involved in the control of gene expression. Bisulfite sequencing of genomic DNA is currently the only method to study DNA methylation patterns at single-nucleotide resolution. Hence, next-generation sequencing of bisulfite-converted...
Autores principales: | Ivanov, Maxim, Kals, Mart, Kacevska, Marina, Metspalu, Andres, Ingelman-Sundberg, Magnus, Milani, Lili |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616706/ https://www.ncbi.nlm.nih.gov/pubmed/23325842 http://dx.doi.org/10.1093/nar/gks1467 |
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