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Transcribed pseudogene ψPPM1K generates endogenous siRNA to suppress oncogenic cell growth in hepatocellular carcinoma
Pseudogenes, especially those that are transcribed, may not be mere genomic fossils, but their biological significance remains unclear. Postulating that in the human genome, as in animal models, pseudogenes may function as gene regulators through generation of endo-siRNAs (esiRNAs), antisense RNAs o...
Autores principales: | Chan, Wen-Ling, Yuo, Chung-Yee, Yang, Wen-Kuang, Hung, Shih-Ya, Chang, Ya-Sian, Chiu, Chien-Chih, Yeh, Kun-Tu, Huang, Hsien-Da, Chang, Jan-Gowth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616710/ https://www.ncbi.nlm.nih.gov/pubmed/23376929 http://dx.doi.org/10.1093/nar/gkt047 |
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