Structural and mechanical properties of individual human telomeric G-quadruplexes in molecularly crowded solutions

Recent experiments provided controversial observations that either parallel or non-parallel G-quadruplex exists in molecularly crowded buffers that mimic cellular environment. Here, we used laser tweezers to mechanically unfold structures in a human telomeric DNA fragment, 5′-(TTAGGG)(4)TTA, along t...

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Detalles Bibliográficos
Autores principales: Dhakal, Soma, Cui, Yunxi, Koirala, Deepak, Ghimire, Chiran, Kushwaha, Saurabh, Yu, Zhongbo, Yangyuoru, Philip M., Mao, Hanbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616730/
https://www.ncbi.nlm.nih.gov/pubmed/23396442
http://dx.doi.org/10.1093/nar/gkt038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616730/
https://www.ncbi.nlm.nih.gov/pubmed/23396442
http://dx.doi.org/10.1093/nar/gkt038

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