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Structural and mechanical properties of individual human telomeric G-quadruplexes in molecularly crowded solutions

Recent experiments provided controversial observations that either parallel or non-parallel G-quadruplex exists in molecularly crowded buffers that mimic cellular environment. Here, we used laser tweezers to mechanically unfold structures in a human telomeric DNA fragment, 5′-(TTAGGG)(4)TTA, along t...

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Detalles Bibliográficos
Autores principales:	Dhakal, Soma, Cui, Yunxi, Koirala, Deepak, Ghimire, Chiran, Kushwaha, Saurabh, Yu, Zhongbo, Yangyuoru, Philip M., Mao, Hanbin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616730/ https://www.ncbi.nlm.nih.gov/pubmed/23396442 http://dx.doi.org/10.1093/nar/gkt038

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