Structured association analysis leads to insight into Saccharomyces cerevisiae gene regulation by finding multiple contributing eQTL hotspots associated with functional gene modules

BACKGROUND: Association analysis using genome-wide expression quantitative trait locus (eQTL) data investigates the effect that genetic variation has on cellular pathways and leads to the discovery of candidate regulators. Traditional analysis of eQTL data via pairwise statistical significance tests...

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Detalles Bibliográficos
Autores principales: Curtis, Ross E, Kim, Seyoung, Woolford Jr, John L, Xu, Wenjie, Xing, Eric P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616858/
https://www.ncbi.nlm.nih.gov/pubmed/23514438
http://dx.doi.org/10.1186/1471-2164-14-196

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