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Differential Association of the Conserved SUMO Ligase Zip3 with Meiotic Double-Strand Break Sites Reveals Regional Variations in the Outcome of Meiotic Recombination

During the first meiotic prophase, programmed DNA double-strand breaks (DSBs) are distributed non randomly at hotspots along chromosomes, to initiate recombination. In all organisms, more DSBs are formed than crossovers (CO), the repair product that creates a physical link between homologs and allow...

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Detalles Bibliográficos
Autores principales: Serrentino, Maria-Elisabetta, Chaplais, Emmanuel, Sommermeyer, Vérane, Borde, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616913/
https://www.ncbi.nlm.nih.gov/pubmed/23593021
http://dx.doi.org/10.1371/journal.pgen.1003416

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