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Rtt109 Prevents Hyper-Amplification of Ribosomal RNA Genes through Histone Modification in Budding Yeast

The genes encoding ribosomal RNA are the most abundant in the eukaryotic genome. They reside in tandem repetitive clusters, in some cases totaling hundreds of copies. Due to their repetitive structure, ribosomal RNA genes (rDNA) are easily lost by recombination events within the repeated cluster. We...

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Detalles Bibliográficos
Autores principales: Ide, Satoru, Saka, Kimiko, Kobayashi, Takehiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616922/
https://www.ncbi.nlm.nih.gov/pubmed/23593017
http://dx.doi.org/10.1371/journal.pgen.1003410

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