Drosophila DJ-1 Decreases Neural Sensitivity to Stress by Negatively Regulating Daxx-Like Protein through dFOXO

DJ-1, a Parkinson's disease (PD)–associated gene, has been shown to protect against oxidative stress in Drosophila. However, the molecular mechanism underlying oxidative stress-induced phenotypes, including apoptosis, locomotive defects, and lethality, in DJ-1-deficient flies is not fully under...

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Detalles Bibliográficos
Autores principales: Hwang, Soojin, Song, Saera, Hong, Yoon Ki, Choi, Gahee, Suh, Yoon Seok, Han, Seung Yeop, Lee, Minjung, Park, Seung Hwan, Lee, Jang Ho, Lee, Soojin, Bang, Se Min, Jeong, Yuji, Chung, Won-Ju, Lee, Im-Soon, Jeong, Gilsang, Chung, Jongkyeong, Cho, Kyoung Sang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616925/
https://www.ncbi.nlm.nih.gov/pubmed/23593018
http://dx.doi.org/10.1371/journal.pgen.1003412

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