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Longitudinal analysis of ear infection and hearing impairment: findings from 6-year prospective cohorts of Australian children
BACKGROUND: Middle ear infection is common in childhood. Despite its prevalence, there is little longitudinal evidence about the impact of ear infection, particularly its association to hearing loss. By using 6-year prospective data, we investigate the onset and impact over time of ear infection in...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616953/ https://www.ncbi.nlm.nih.gov/pubmed/23432915 http://dx.doi.org/10.1186/1471-2431-13-28 |
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author | Yiengprugsawan, Vasoontara Hogan, Anthony Strazdins, Lyndall |
author_facet | Yiengprugsawan, Vasoontara Hogan, Anthony Strazdins, Lyndall |
author_sort | Yiengprugsawan, Vasoontara |
collection | PubMed |
description | BACKGROUND: Middle ear infection is common in childhood. Despite its prevalence, there is little longitudinal evidence about the impact of ear infection, particularly its association to hearing loss. By using 6-year prospective data, we investigate the onset and impact over time of ear infection in Australian children. METHODS: We analyse 4 waves of the Longitudinal Study of Australian Children (LSAC) survey collected in 2004, 2006, 2008, and 2010. There are two age cohorts in this study (B cohort aged 0/1 to 6/7 years N=4242 and K cohort aged 4/5 to 10/11 years N=4169). Exposure was parent-reported ear infection and outcome was parent-reported hearing problems. We modelled ear infection onset and subsequent impact on hearing using multivariate logistic regressions, reporting Adjusted Odds Ratios (AOR) and Confidence Intervals (95% CI). Separate analyses were reported for indigenous and non-indigenous children. RESULTS: Associations of ear infections between waves were found to be very strong both among both indigenous and non-indigenous children in the two cohorts. Reported ear infections at earlier wave were also associated with hearing problems in subsequent wave. For example, reported ear infections at age 4/5 years among the K cohort were found to be predictors of hearing problems at age 8/9 years (AOR 4.0, 95% CI 2.2-7.3 among non-indigenous children and AOR 7.7 95% CI 1.0-59.4 among indigenous children). Number of repeated ear infections during the 6-year follow-up revealed strong dose–response relationships with subsequent hearing problems among non-indigenous children (AORs ranged from 4.4 to 31.7 in the B cohort and 4.4 to 51.0 in the K cohort) but not statistically significant among indigenous children partly due to small sample. CONCLUSIONS: This study revealed the longitudinal impact of ear infections on hearing problems in both indigenous and non-indigenous children. These findings highlight the need for special attention and follow-up on children with repeated ear infections. |
format | Online Article Text |
id | pubmed-3616953 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-36169532013-04-05 Longitudinal analysis of ear infection and hearing impairment: findings from 6-year prospective cohorts of Australian children Yiengprugsawan, Vasoontara Hogan, Anthony Strazdins, Lyndall BMC Pediatr Research Article BACKGROUND: Middle ear infection is common in childhood. Despite its prevalence, there is little longitudinal evidence about the impact of ear infection, particularly its association to hearing loss. By using 6-year prospective data, we investigate the onset and impact over time of ear infection in Australian children. METHODS: We analyse 4 waves of the Longitudinal Study of Australian Children (LSAC) survey collected in 2004, 2006, 2008, and 2010. There are two age cohorts in this study (B cohort aged 0/1 to 6/7 years N=4242 and K cohort aged 4/5 to 10/11 years N=4169). Exposure was parent-reported ear infection and outcome was parent-reported hearing problems. We modelled ear infection onset and subsequent impact on hearing using multivariate logistic regressions, reporting Adjusted Odds Ratios (AOR) and Confidence Intervals (95% CI). Separate analyses were reported for indigenous and non-indigenous children. RESULTS: Associations of ear infections between waves were found to be very strong both among both indigenous and non-indigenous children in the two cohorts. Reported ear infections at earlier wave were also associated with hearing problems in subsequent wave. For example, reported ear infections at age 4/5 years among the K cohort were found to be predictors of hearing problems at age 8/9 years (AOR 4.0, 95% CI 2.2-7.3 among non-indigenous children and AOR 7.7 95% CI 1.0-59.4 among indigenous children). Number of repeated ear infections during the 6-year follow-up revealed strong dose–response relationships with subsequent hearing problems among non-indigenous children (AORs ranged from 4.4 to 31.7 in the B cohort and 4.4 to 51.0 in the K cohort) but not statistically significant among indigenous children partly due to small sample. CONCLUSIONS: This study revealed the longitudinal impact of ear infections on hearing problems in both indigenous and non-indigenous children. These findings highlight the need for special attention and follow-up on children with repeated ear infections. BioMed Central 2013-02-21 /pmc/articles/PMC3616953/ /pubmed/23432915 http://dx.doi.org/10.1186/1471-2431-13-28 Text en Copyright © 2013 Yiengprugsawan et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Yiengprugsawan, Vasoontara Hogan, Anthony Strazdins, Lyndall Longitudinal analysis of ear infection and hearing impairment: findings from 6-year prospective cohorts of Australian children |
title | Longitudinal analysis of ear infection and hearing impairment: findings from 6-year prospective cohorts of Australian children |
title_full | Longitudinal analysis of ear infection and hearing impairment: findings from 6-year prospective cohorts of Australian children |
title_fullStr | Longitudinal analysis of ear infection and hearing impairment: findings from 6-year prospective cohorts of Australian children |
title_full_unstemmed | Longitudinal analysis of ear infection and hearing impairment: findings from 6-year prospective cohorts of Australian children |
title_short | Longitudinal analysis of ear infection and hearing impairment: findings from 6-year prospective cohorts of Australian children |
title_sort | longitudinal analysis of ear infection and hearing impairment: findings from 6-year prospective cohorts of australian children |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616953/ https://www.ncbi.nlm.nih.gov/pubmed/23432915 http://dx.doi.org/10.1186/1471-2431-13-28 |
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