Cargando…

Delay-dependent impairment of spatial working memory with inhibition of NR2B-containing NMDA receptors in hippocampal CA1 region of rats

Hippocampal N-methyl-D-aspartate receptor (NMDAR) is required for spatial working memory. Although evidence from genetic manipulation mice suggests an important role of hippocampal NMDAR NR2B subunits (NR2B-NMDARs) in spatial working memory, it remains unclear whether or not the requirement of hippo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Xue-Han, Liu, Shu-Su, Yi, Feng, Zhuo, Min, Li, Bao-Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616959/ https://www.ncbi.nlm.nih.gov/pubmed/23497405 http://dx.doi.org/10.1186/1756-6606-6-13

Ejemplares similares

Induction- and conditioning-protocol dependent involvement of NR2B-containing NMDA receptors in synaptic potentiation and contextual fear memory in the hippocampal CA1 region of rats
por: Zhang, Xue-Han, et al.
Publicado: (2008)

Zinc enhances hippocampal long-term potentiation at CA1 synapses through NR2B containing NMDA receptors
por: Sullivan, John A., et al.
Publicado: (2018)

Plasticity of NMDA receptor NR2B subunit in memory and chronic pain
por: Zhuo, Min
Publicado: (2009)

Blockade of NR2A-Containing NMDA Receptors Induces Tau Phosphorylation in Rat Hippocampal Slices
por: Allyson, Julie, et al.
Publicado: (2010)

A role for hippocampal PSA-NCAM and NMDA-NR2B receptor function in flavonoid-induced spatial memory improvements in young rats
por: Rendeiro, Catarina, et al.
Publicado: (2014)

Impaired spatial working memory but spared spatial reference memory following functional loss of NMDA receptors in the dentate gyrus
por: Niewoehner, B, et al.
Publicado: (2007)

Chronic Zinc Exposure Decreases the Surface Expression of NR2A-Containing NMDA Receptors in Cultured Hippocampal Neurons
por: Zhu, Jia, et al.
Publicado: (2012)

Pharmacological isolation of postsynaptic currents mediated by NR2A- and NR2B-containing NMDA receptors in the anterior cingulate cortex
por: Wu, Long-Jun, et al.
Publicado: (2007)

The lateralization of left hippocampal CA3 during the retrieval of spatial working memory
por: Song, Da, et al.
Publicado: (2020)

Hippocampal NMDA receptors are important for behavioural inhibition but not for encoding associative spatial memories
por: Taylor, A. M., et al.
Publicado: (2014)

Transection of the ventral hippocampal commissure impairs spatial reference but not contextual or spatial working memory
por: Jordan, Jake T., et al.
Publicado: (2022)

Abeta(1-42) Enhances Neuronal Excitability in the CA1 via NR2B Subunit-Containing NMDA Receptors
por: Varga, Edina, et al.
Publicado: (2014)

Synaptic NR2A- but not NR2B-Containing NMDA Receptors Increase with Blockade of Ionotropic Glutamate Receptors
por: von Engelhardt, Jakob, et al.
Publicado: (2009)

Potentiation of Glycine-Gated NR1/NR3A NMDA Receptors Relieves Ca(2+)-Dependent Outward Rectification
por: Madry, Christian, et al.
Publicado: (2010)

Requirement for hippocampal CA3 NMDA receptors in artificial association of memory events stored in CA3 cell ensembles
por: Nomoto, Masanori, et al.
Publicado: (2023)

Residues at the tip of the pore loop of NR3B-containing NMDA receptors determine Ca(2+ )permeability and Mg(2+ )block
por: Cavara, Nora A, et al.
Publicado: (2010)

Correction: Requirement for hippocampal CA3 NMDA receptors in artificial association of memory events stored in CA3 cell ensembles
por: Nomoto, Masanori, et al.
Publicado: (2023)

The effects of crocin on spatial memory impairment induced by hyoscine: Role of NMDA, AMPA, ERK, and CaMKII proteins in rat hippocampus
por: Adabizadeh, Maliheh, et al.
Publicado: (2019)

Surface expression of hippocampal NMDA GluN2B receptors regulated by fear conditioning determines its contribution to memory consolidation in adult rats
por: Sun, Yan-Yan, et al.
Publicado: (2016)

Lupus autoantibodies act as positive allosteric modulators at GluN2A-containing NMDA receptors and impair spatial memory
por: Chan, Kelvin, et al.
Publicado: (2020)

The A-Current Modulates Learning via NMDA Receptors Containing the NR2B Subunit
por: Fontán-Lozano, Ángela, et al.
Publicado: (2011)

Gestational Chronodisruption Impairs Hippocampal Expression of NMDA Receptor Subunits Grin1b/Grin3a and Spatial Memory in the Adult Offspring
por: Vilches, Nelson, et al.
Publicado: (2014)

Impaired spatial working memory and reduced hippocampal neuronal density in a rat model of neurocysticercosis
por: Baquedano, Laura E., et al.
Publicado: (2023)

The Effects of NR2 Subunit-Dependent NMDA Receptor Kinetics on Synaptic Transmission and CaMKII Activation
por: Santucci, David M., et al.
Publicado: (2008)

Dissecting Spatial Knowledge from Spatial Choice by Hippocampal NMDA Receptor Deletion
por: Bannerman, David M., et al.
Publicado: (2012)

Ablation of NMDA Receptors Enhances the Excitability of Hippocampal CA3 Neurons
por: Fukushima, Fumiaki, et al.
Publicado: (2009)

EHMTI-0308. Cortical spreading depression increases NR2A/NR2B ratio by altering numbers of nr2a and nr2b subunit-containing nmda receptors in the hippocampus
por: Hansrivijit, P, et al.
Publicado: (2014)

d-Aspartate consumption selectively promotes intermediate-term spatial memory and the expression of hippocampal NMDA receptor subunits
por: Zachar, Gergely, et al.
Publicado: (2021)

Long-Term Potentiation in the CA1 Hippocampus Induced by NR2A Subunit-Containing NMDA Glutamate Receptors Is Mediated by Ras-GRF2/Erk Map Kinase Signaling
por: Jin, Shan-xue, et al.
Publicado: (2010)

Dorsal hippocampal CA1 NMDA receptors mediate the interactive effects of quetiapine and lithium on memory retention in male rats
por: Jafari-Sabet, Majid, et al.
Publicado: (2023)

Structural correlates of impaired working memory in hippocampal sclerosis
por: Winston, Gavin P, et al.
Publicado: (2013)

Delayed-matching-to-position working memory in mice relies on NMDA-receptors in prefrontal pyramidal cells
por: Kilonzo, Kasyoka, et al.
Publicado: (2021)

Involvement of spinal NR2B-containing NMDA receptors in oxaliplatin-induced mechanical allodynia in rats
por: Mihara, Yuki, et al.
Publicado: (2011)

Hippocampal-prefrontal input supports spatial encoding in working memory
por: Spellman, Timothy, et al.
Publicado: (2015)

Cingulate NMDA NR2B receptors contribute to morphine-induced analgesic tolerance
por: Ko, Shanelle W, et al.
Publicado: (2008)

Left−Right Asymmetry Defect in the Hippocampal Circuitry Impairs Spatial Learning and Working Memory in iv Mice
por: Goto, Kazuhiro, et al.
Publicado: (2010)

Effects of electromagnetic radiation on spatial memory and synapses in rat hippocampal CA1☆
por: Li, Yuhong, et al.
Publicado: (2012)

The Neurogenesis Actuator and NR2B/NMDA Receptor Antagonist Ro25-6981 Consistently Improves Spatial Memory Retraining Via Brain Region-Specific Gene Expression
por: Gruden, Marina A., et al.
Publicado: (2018)

Neuroprotective Mechanisms of Lycium barbarum Polysaccharides Against Ischemic Insults by Regulating NR2B and NR2A Containing NMDA Receptor Signaling Pathways
por: Shi, Zhongshan, et al.
Publicado: (2017)

A role of periaqueductal grey NR2B-containing NMDA receptor in mediating persistent inflammatory pain
por: Hu, Jing, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_ql4kcaf9f7gh8gdh1r5ul2nse6